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    Principles of Chemical Synthesis
    CHEM S345
      More information: Course Guide
    Principles of Chemical Synthesis
    Course Start Date
    Spr 2023
    Course Level
    Length in Terms
    1 term
    Fees ($) (including lab fees)
    Future Terms
    Start Date
    Course Level Length in Terms Credits
    Fees ($)
    (including lab fees)
    Future Terms
    Spr 2023
    Higher 1 term 5

    Course Coordinator: Dr Chen Jianlin, BSc (TJU), MSc (TJU), Ph.D. (CityU)

    Course Developer: The Open University, UK, Course Team

    This course deals with the strategy of organic synthesis, with particular emphasis on selectivity and synthetic design. It introduces a wide variety of the modern chemical reactions now available to the organic chemist and includes some of the methods and techniques for the isolation and identification of pure compounds. Case studies on solid-phase synthesis, including combinatorial methods, insect pheromones, prostaglandins and beta-lactams, reinforce the many facets of the complex process involved in the design and preparation of such substances.

    Advisory prerequisite(s)
    You are advised to have completed CHEM S251 or have some background knowledge in organic chemistry.

    This course aims to provide you with knowledge of chemistry and organic synthesis concerning skills, strategies, and case studies in these areas. The course will also emphasize the interdisciplinary nature of organic chemistry and its application to society.

    Topics to be covered in the course:

    • Fundamental of organic synthesis

    • Electronic and steric effects on stereochemical outcomes of reaction

    • Strategy, disconnection, and selectivity

    • Functional group interconversions

    • Reagents for synthesis

    • Quantification of drug activity

    • Case studies on enzymes, inhibitors and receptors

    Learning support
    There are regular tutorials and surgeries with your tutors throughout the course.

    Laboratory classes
    Regular laboratory sessions will be arranged during the course where tutors and supervisors will guide you through the experiments related to the course content.

    Three assignments are designed to assess your progress in the course. All assignments will be counted to the overall continuous assignment score. There will be a three-hour final course examination at the end of the course. Students are required to submit assignments via the Online Learning Environment (OLE).

    Online support
    This course is supported by the Online Learning Environment (OLE). You can find the latest course information from the OLE. Through the OLE, you can communicate electronically with your tutor and the Course Coordinator as well as other students. To access the OLE, students will need to have access to the Internet.

    Students need access to a personal computer or other electronic devices with an internet connection.

    Set book(s)

    Two textbooks will be provided.

    Students with disabilities or special educational needs
    This course contains visual and audio materials that you have to work through in order to complete your studies successfully. You are encouraged to seek further advice from the Course Coordinator if you feel that will be physically challenging.

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